Monday, 21st October Australasian RNA Biology and Biotechnology Association 2024 Conference

Large-scale studies of RNA binding proteins provides a lens into human diseases and therapeutics - Gene Yeo

Note: Due to a scheduling conflict, Gene will not be at A-RNA in person, but will delivery a live presentation virtually.

Keynote Session Sponsor:

• DEAD-box ATPases as regulators of biomolecular condensates and membrane-less organelles - Maria Hondele
• Nuclear export of circular RNA - Hoang Linh Ngo
• RNA subcellular real-time translation dynamics direct cell fates from the second polar body to inner cell allocation during early mammalian embryogenesis   - Hongbin Jin
• THE TREX-2 COMPLEX IS AN UNIDENTIFIED mRNA EXPORT RECEPTOR - Yoona Kim

• RNA-binding proteins: a computational approach to investigate interaction modes and the potential for targeted disruption. - Jameel M. Abduljalil
• Age-Related Changes in Circular RNAs and their Interactions with microRNAs in the Human Posterior Cingulate Cortex - Fatemeh Amjadimoheb
• The role of  long-non coding RNA NKAPP1 in neuroblastoma - Dian Anggraini
• First report of RNA editing in a large human retina cohort reveals genetic drivers of degenerative disease - Brendan R E Ansell
• ADAR-RADAR Development of a scalable pipeline for RNA editing detection and annotation in RNA-seq data  - Brendan R E Ansell
• Design and optimization of messenger mRNA with large language models for enhanced protein translation. - Sai Surya Teja Bhogaraju
• THE MAMMALIAN OOCYTE AS A CELL SYSTEM TO STUDY TEMPORAL CONTROL OF RNA STORAGE AND CYTOPLASMIC POLYADENYLATION - Lemia Bickalo
• Using CRISPR-cas13 to identify functional lncRNAs in breast cancer - Maina Bitar
• Combinatorial small RNAs are effective and specific in targeting RAS-dependent cancers - Cameron P Bracken
• Characterisation of the role of nuclear actin for intranuclear mRNA transport - Kirstyn Carey
• mRNA-vaccines and antibodies to combat Flavivirus infections - Julio Carrera Montoya
• mRNA Design and Production: A Streamlined Approach to Accelerate Vaccine and Therapy Development - Natasha Chaudhary
• A Versatile Method to Improve Cell Targeting and mRNA Expression by Controlling the Orientation of Antibodies on Lipid Nanoparticles (LNPs). - Moore Zhe MC Chen
• Unraveling the Complexity: A Review on the Accurate Detection of Isoforms and Alternative Splicing using RNA Sequencing - Qingwang Chen
•   Developing mRNA-based Human T-cell Leukemia Virus type 1 (HTLV-1) Virus-like particle as a vaccine candidate - Yuanhao Chen
• Viral riboswitch structures as therapeutic targets - Vincent Corbin
• Nanoparticle generation for drug delivery - something old, something new, most are borrowed – rarely blue. - Peter Davis
• Lyophilized Ionizable Lipid Nanoparticles for mRNA Delivery - Sarah Draper
• RNA binding domain of the trim NHL-2 is required for its function - Fahimeh Eskandari
• Understanding the role of eIF4E-binding protein IFET-1 in RNA-protein complex formation - Marziye Farsi Madan
• Plasmodium falciparum as a Model Organism for Studies on mRNA Modifications - Lakvin Fernando
• Isoform-level profiling of m6A epitranscriptomic signatures in human brain - Josie Gleeson
• Exploring the role of IRES-containing, m⁶A-modified circular RNAs in the formation of fear extinction memory - Hao Gong
• Developing intracellular antibody therapies for liver diseases - Deepagan Gopal
• Investigation of long non-coding RNAs as potential tumor suppressors in triple-negative breast cancer - Joke Grans
• DEVELOPING AUTOMATED COMPUTATIONAL METHODS FOR INVESTIGATING KEY COMPONENTS OF VERTEBRATE ENHANCER SEQUENCES. - Mia Gruzin
• Substrate diversity of NSUN enzymes and links of 5-methylcytosine to mRNA translation and turnover - Marco Guarnacci
• A novel RNA export mechanism regulates early developmental models - William B Hamilton
• Sequencing of nascent RNAs at single molecule resolution reveals new insights into RNA processing and modification timing. - Rippei Hayashi
• Understanding the correlations between pKa and cytosolic delivery of lipid nanoparticles  - Yujia He
• The apparent loss of PRC2 chromatin occupancy as an artifact of RNA depletion - Evan Healy
• GGNBP2 regulates self-sensing of cellular dsRNA following loss of ADAR1 - Jacki Heraud-Farlow
• Direct RNA sequencing via nanopore technology reveals mRNA post-transcriptional modifications in virus-infected host cells - Md Zohorul Islam
• Exquisite Timing and Mechanistic Diversity of Gene Expression Change in Response to Nutritional Stress in Saccharomyces cerevisiae - Yoshika Janapala
• Upf1 Regulation of mRNA Decay During Brain Development - Lachlan A Jolly
• Investigating the role of mRNA translational reprogramming in mediating drug resistance in ovarian cancer - Jian Kang
• Auto-inhibition of PRC2 by the broadly expressed long isoform of AEBP2. - Zhihao lai
• Identifying m⁶A sites in Plasmodium falciparum mRNA with Nanopore signal analysis - Joshua M Levendis
• Revealing gene isoforms in cortical development: Insights into neuropsychiatric disorder risk - Anran Li
• Engineering multi-targeted biodegrader intrabodies to treat necroptotic-driven diseases - Hugh Ma
• New Zealand's RNA Platform: Research, Development, and Updates - Caitlin MacArthur
• Identification of Potent Tumor Suppressor miRNAs for Therapeutic Intervention in Hepatocellular Carcinoma: Insights from Lethal Screen - Khadijeh KM Mahboobnia
• Leveraging microRNA length isoforms to improve microRNA biomarker performance - Alexandra L McAllan
• Regulation of splicing in a human malaria parasite - Emma McHugh
• Developing macrocyclic peptide inhibitors against a bacterial receptor for antibiotic leads - Madeline S McRae
• Vaults as Trafficking Granules in Fear Learning - Mason R B Musgrove
• Extracellular vesicles-derived microRNAs in thrombocytopenia - Attakorn Palasuwan
• Serum microRNAs as new biomarkers for detecting subclinical hemolysis in the nonacute phase of G6PD deficiency - Duangdao Palasuwan
•  Reference Materials Traceable to SI units for RNA Quantification Harmonisation  - Leo Dr Pinheiro
• Unlocking the Hidden World of RNA Isoforms: Insights from Long-Read Single-Cell Sequencing in Neurogenesis - Sefi Prawer
• Antivirals Targeting the Conserved HIV-1 TIM-TAM Riboswitch Specifically Reactivate HIV-1 from Latency through Modulating Viral RNA-biology. - Leigh Harty
• Human RNase 4 improves mRNA characterization by LC–MS/MS  - Selva Kumari Ramasubramanian
• Three activities, one enzyme: Understanding the Faustovirus RNA capping enzyme mechanism - Selva Kumari Ramasubramanian
• A Novel Transcript Derived from Extrachromosomal Circular DNA is Critical for Fear Extinction Memory - Haobin Ren
• The evolution of transcriptome complexity using Oxford Nanopore long-read sequencing technology.  - Gabriela Santos-Rodriguez
• Integration of multimodal RNA processing data reveals substoichiometric transcriptome regulation   - Aditya J. Sethi
• Improving the diagnosis and treatment of cancer with long non-coding RNAs - Martin A Smith
• Development and optimisation of 3-base oligonucleotide therapeutics targeting TLR7 and TLR8 - Mary Speir
• Pan-cancer analysis links RNA m7G methyltransferase expression link to oncogenic pathways, immune cell infiltrations and overall survival in human cancer - Anni Su
• Evaluation the reproducibility of m⁶A peak calls across public databases - Gavin J Sutton
• Comparison of ionisable cationic and PEG lipids formulated in LNP-mRNA vaccines against the XBB.1.5 (Omicron) SARS-CoV-2 Strain - Asuka Takanashi
• Finding treatments for chromatin disorders: early postnatal interventions to improve neurodevelopmental outcomes - Hannah Vanyai
• ADAR1p150 protein, independent of its A-to-I RNA editing activity, regulates peripheral haematopoietic homeostasis. - Carl Walkley
• Biomarker and Therapeutic Potential of Circular RNAs in Ovarian Cancer - Sineth Wijekoon-Mudiyanselage
• Dynamic changes in RNA modifications influence gene expression programs during macrophage differentiation and polarisation - Justin Wong
• Expanding neutralising antibody breadth with a polyvalent SARS-CoV-2 mRNA vaccine expressing three linked-RBD domains from different variants - Damian Purcell